Deal brings the
largest cool-season turfgrass and forage seed company together with Kimeragens
Precise Genetic Modification Technology to develop new turf and forage varieties
Newtown, PA and Henderson, NV
December 30, 1998
Kimeragen, Inc.
and AgriBioTech, Inc. ("ABT") (NASDAQ
National Market: ABTX) announced today that they have entered into an exclusive
collaboration to develop turfgrass and forage seed products using Kimeragens
enabling technology platform, "chimeraplasty," that allows for the development
of improved varieties with new desirable traits. Chimeraplasty is referred to as
"precise genetic surgery" because specific genes are selectively modified
without affecting the rest of the genome or altering normal protein expression and cell
function.
Kimeragens enabling technology platform, chimeraplasty,
allows specific repair or replacement of small segments of genes. Chimeraplasty is
applicable to plants, animals, bacteria and human cells. When used in clinical
applications, this molecule is packaged with a delivery system and then is administered
into the subject and ultimately the chimeraplast binds selectively to the portion of the
target gene to be modified. Once bound, chimeraplasty activates the recipients own
gene-correcting mechanism, which mediates the gene change. For plants, the chimeraplast
enters a plant cell, makes the desired genetic change, and the modified cell is then grown
into a full plant that contains the new trait, which is passed to the next generation
through the seed.
ABT will have exclusive rights to Kimeragens technology
for all forage and turfgrass species, subject to two prior non-exclusive licenses. Earlier
ABT announced acquiring a research license to "whiskers" transformation
technology from Garst Seed Company (Advanta), an agreement that gives the Company, at its
option, the opportunity to acquire a commercialization license for products developed with
this technology. The whiskers technology can be used to deliver "chimeraplasts"
into target plant cells.
"This new Kimeragen technology, which can be used to
selectively inactivate genes or to introduce targeted mutations to alter gene function,
provides us with an additional and important tool for developing new products with unique
and valuable
traits," said Dr. Tom Rice, ABT Vice President, Director
of Research, "and it expands and strengthens our biotechnology capabilities and
options."
"We are pleased that the largest cool-season turfgrass
and forage seed company will be applying our unique and proprietary technology in their
seed sector," said Gerald L. Messerschmidt, M.D., President and CEO of Kimeragen.
"We look forward to working with ABT to develop important new products in this area
so that turfgrass and forage seed users can enjoy the benefits of our highly selective
technology for introducing targeted genetic changes."
Kimeragen, Inc., is a privately held company headquartered in
Newtown, PA engaged in the discovery, development and marketing of unique products for
human health, plant and animal/veterinary applications. The company is developing
chimeraplasty as an enabling technology for three distinct business areas: pharmaceuticals
to repair genetic abnormalities implicated in a broad array of human diseases; plants and
industrial products to enhance genetic traits in plants; genomic and transgenic animal
technologies aimed at developing higher value applications and products for human health
and veterinary care. Kimeragen plans to commercialize many of those applications through
partnerships with global leaders in these fields.
AgriBioTech is a fully integrated full service seed company
specializing in the forage and turfgrass seed sector, complete with research and
development of proprietary seed varieties, seed processing plants, and a national and
international distribution and sales network. The Company has completed 33 acquisitions
since January 1, 1995 and is the largest forage and cool-season turfgrass seed company in
the world, with a current level of annualized net sales of approximately $475 million,
including the previously announced pending acquisitions of the alfalfa business and
international sorghum units of AgriPro Seeds, Inc., Moore Seed Processors, and Production
Plus+, which have annualized net sales aggregating approximately $35 million.
The statements discussed in this press release include
forward-looking statements that involve a number of risks and uncertainties. These include
AgriBioTechs historical lack of profitability, need to manage its growth, intense
competition in the seed industry, seasonality of quarterly results, weather conditions,
volatile stock price and other risks detailed from time to time in the Companys SEC
reports.
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