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Icon Genetics announces strategic research alliance with Bayer CropScience

Munich, Germany
January 31, 2005 

Icon Genetics AG (ICON) announced today that it has entered into collaborative agreements with Bayer CropScience to evaluate the expression levels and quality of selected pre-clinical pharmaceutical proteins expressed in highly-specialized plant varieties. Terms of the agreements were not disclosed.

The alliance centers around the utilization of Icon Genetics. proprietary magnICON® biomanufacturing platform technology, which provides a process for producing therapeutic and other high-value recombinant proteins using non-food plants as production hosts. This innovative technology ensures the highest possible yield of a recombinant protein in a plant cell, and allows for rapid production of adequate quantities of such proteins as necessary for clinical trials, thus eliminating many conventional research, development and production constraints. The technology is also fully scalable and biosafe, as it relies on fully contained (greenhouse) plant cultivation.

"We welcome this relationship with Bayer CropScience, a global industry leader," said Yuri Gleba, CEO of Icon Genetics. "This collaboration is expected to create very significant product development and manufacturing opportunities for both companies."

Bayer CropScience, a subsidiary of Bayer AG with annual sales of about EUR 5.8 billion (2003), is one of the world's leading innovative crop science companies in the areas of crop protection, non-agricultural pest control, seeds and plant biotechnology. The company offers an outstanding range of products and extensive service backup for modern, sustainable agriculture and for non-agricultural applications. Bayer CropScience has a global workforce of about 19,000 and is represented in more than 120 countries, ensuring proximity to dealers and consumers.

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