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NEWS

Monsanto licenses the Rosetta Resolver gene expression data analysis system

Kirkland, Washington
June 27,  2001

Rosetta Inpharmatics, Inc. (Nasdaq:RSTA), a leading developer of gene expression data analysis software, and Agilent Technologies Inc. (NYSE:A) today announced that Monsanto Company (NYSE:MON) has licensed the Rosetta Resolver(R) Gene Expression Data Analysis System.

The Rosetta Resolver system is a bioinformatics system for gene expression research developed by Rosetta Inpharmatics and exclusively distributed by Agilent. The Rosetta Resolver system can be used with a variety of third-party and internally developed DNA microarray technologies, including Affymetrix GeneChip(R)probe arrays and Agilent DNA microarrays.

"Monsanto's goal is to provide top-quality, cost-effective and integrated approaches to help farmers improve their productivity and produce better quality foods," said Dr. Christine Karslake, director of business development of Monsanto Company. "The Rosetta Resolver system, which will empower us to conduct thorough and rapid analysis of our gene expression data, has comprehensive features and high quality statistics that can help us to quickly and efficiently develop products and solutions to achieve our goal."

"We are pleased to add the world's leading provider of agricultural solutions to our esteemed list of Rosetta Resolver system customers," said Bill Buffington, vice president and general manager of Agilent Technologies' Life Sciences Division. "Monsanto joins three of the top pharmaceutical companies and three of the top biotechnology companies who have been enabled with the most comprehensive, robust tool for gene expression data analysis."

About the Rosetta Resolver System

The Rosetta Resolver system provides high-capacity data storage, retrieval and analysis of gene expression data. The system is ideal for life science research organizations that need to assess compound specificity or toxicity, identify new genes or therapeutic targets, or compare and analyze large databases of expression profiles. The Rosetta Resolver system combines flexibility and ease of use with high-performance algorithms to produce an enterprise solution for rapid
analysis of gene expression data. The system can accept and analyze data from a wide variety of expression profiling formats, including Affymetrix GeneChip Probe Arrays and Agilent DNA microarrays, and applies Rosetta Inpharmatics' proprietary error models to yield quality statistics for every gene expression measurement. These statistics are automatically leveraged by all analysis tools, ensuring reliable results. In addition to Monsanto, many of the world's leading life science organizations have licensed the Rosetta Resolver system, including Biogen, DuPont Pharmaceuticals, GlaxoSmithKline, and the Harvard University Center for Genomics Research. Additional information about the Rosetta Resolver system can be found on Rosetta Inpharmatics' Web site at www.rii.com

About Agilent Technologies

Agilent Technologies Inc. (NYSE:A) is a global technology leader in communications, electronics, life sciences and healthcare. With 48,000 employees serving customers in more than 120 countries, Agilent had net revenue of $10.8 billion in fiscal year 2000. Information about Agilent can be found on the Web at www.agilent.com

About Rosetta Inpharmatics

Founded in December 1996, Rosetta Inpharmatics (Nasdaq:RSTA) is an early leader in gene expression analysis. Its technology solutions, including the Rosetta Resolver system, are designed for many purposes, such as the potential to accelerate drug discovery and agricultural product development by improving biological data analysis. Gene expression analysis is instrumental in many aspects of drug discovery and agricultural product development. Information about Rosetta Inpharmatics can be found on the Web at www.rii.com.

Resolver is a registered trademark of Rosetta Inpharmatics, Inc.
GeneChip is a registered trademark of Affymetrix, Inc.

Company news release
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