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About Cibus

Founded in 2001, Cibus is a privately-held San Diego-based trait development company that produces environmentally-friendly crop traits for the agricultural community. Through the application of a proprietary technology called the Rapid Trait Development System (RTDS™), Cibus yields traits that are free of the market-resistance and regulatory burden of attributes engineered using the introduction of foreign genetic material. RTDS has proven itself in the laboratory with several different crops as well as in the initial field trials of Cibus’ first commercial crop.

About Cibus’ RTDS technology

RTDS is an environmentally-safe, smart-breeding technology that enables seed producers to develop plants with commercially valuable characteristics. Unlike genetic engineering—which produces GMO crops by inserting exotic genetic material from one species into another—RTDS introduces genetic traits through a natural process of gene repair within the very same plant species. RTDS operates exclusively within the genome of the plant, just like normal plant breeding, and thus eliminates environmental and health risks as well as other unintended and unknown consequences associated with GMO crops.

Cibus technology produces changes within a plant species that could only occur in nature, but it does so in a focused way. Thanks in part to recent advancements in genome mapping that have illuminated many gene targets, RTDS is more precise and much faster than traditional hit-and-miss plant breeding (with or without marker assisted selection) and transgenic breeding technology, both of which can take years to perfect a trait. Cibus technology delivers the advantages that farmers seek in GMO crops such as herbicide tolerance or increased yield and benefits from the clear path to market and consumer confidence of traditionally bred plants. Cibus’ regulatory advantage and the speed of this plant breeding technology promise the greatly accelerated development of new value added traits in readily accepted crops.

The RTDS process, also known as directed mutagenesis, works through the cell’s natural process of gene repair. Every time a cell copies DNA, it makes “scrivener” errors or spelling mistakes. These variations happen all the time, which is how natural variation occurs. Cibus’ technology harnesses the cell’s own natural DNA repair machinery to correct such spelling mistakes, thus directing DNA repair enzymes to correct and repair the targeted gene in a specific way in order to produce a desired trait. The process, in its precision, is similar to altering a letter in a single word contained within a large book. Nothing in the genome is altered by this approach other than the changes directed by the process.

www.cibus.com


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