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New method for better profiling of GM plants

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Madrid, Spain
June 28, 2007

Source: GMO Compass

Spanish scientists have developed a new technique that may result in better nutritional and safety profiles for the next generation of genetically modified plants. The method has been published in the recent issue of the scientific magazine Analytical Chemistry and analyses potential changes in the amino acid composition of transgenic crops.

The new technique may be of great interest for industry and consumers alike, since it potentially improves nutritional and safety profiling of transgenic crops and shows how they may differ from their conventional counterparts. "The analysis demonstrated for the first time that it can be used as an additional indicator in assessing the existence of unexpected modifications in metabolic pathways linked to the amino acid profile within a GMO," wrote researchers.

Amino acids are the building blocks of proteins. Herrero and co-workers were able to analyse the amino acid composition in less than 25 minutes, and found that conventional maize varieties show different profiles, reflecting the variability expected from nature. Comparison with corresponding transgenic Bt maize varieties found no significant difference. "This result seems to indicate that, in these maize samples, the new inserted Cry1Ab transgene has not modified any metabolic pathway linked to the detected amino acids, which seems to add a further proof of the safety equivalence of these samples," stated researchers.


Analytical Chemistry publication
Analysis of Chiral Amino Acids in Conventional and Transgenic Maize
Miguel Herrero, Elena Iba´n˜ ez, Pedro J. Martı´n-AÄ lvarez, and Alejandro Cifuentes
Institute of Industrial Fermentations (CSIC), Juan de la Cierva 3, 28006 Madrid, Spain

http://pubs.acs.org/cgi-bin/sample.cgi/ancham/asap/pdf/ac070454f.pdf

 

 

 

 

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