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Kansas State University, Texas A&M researchers boost lettuce calcium content

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Manhattan, Kansas
January 23, 2009

Led by 87 percent of the nation´s teenage girls and 78 percent of U.S. women age 20 or older, today´s average American eats far too little calcium - the most abundant mineral in the human body.

Calcium is best known for its role in deciding the lifelong, year-to-year strength or weakness of bones and teeth. The fact is, however, calcium intake is crucial to every bodily function, from nerves and muscles to glands and blood vessels.

That´s why plant scientists at Kansas State and Texas A&M universities are working to make meeting daily calcium needs easier. Their plan is to expand people´s range of calcium-rich food choices.

"Thus far, few vegetables are good sources of calcium. And, those few aren´t a significant part of the average U.S. diet," said Sunghun Park, K-State horticulturist and the project´s lead scientist.

The researchers´ first results include a 25 to 32 percent hike in the in-bred calcium supplied by common leaf lettuce. The team now hopes to raise their lettuce lines´ nutrient value even further.

Today, most of the calcium Americans eat comes from such dairy products as milk, yogurt and cheese, according to the Office of the Surgeon General. Some also comes from "fortified" products (orange juice, bread, cereals) and such dark, leafy greens as bok choy, collards and broccoli.

"To expand that list, we´re using a strategy called biofortification. We´re working to genetically improve what we know are popular vegetables, to make them more nutrient-dense," Park said.

The researchers´ first report says their biofortified leaf lettuce lines are reproducing true to form and growing robustly under greenhouse conditions. Yet, the report emphasizes a different finding.

In an unusual move, the researchers submitted their "new" lettuce to the Sensory Analysis Center in K-State´s Department of Human Nutrition. And, a panel of scientific evaluators there found the enhanced lettuce to be no different from "regular" leaf lettuce in flavor, bitterness or crispness.

"In other words, if you were to encounter both of them in a salad or hamburger, you wouldn´t be able to tell which was which. That could make a big difference in public acceptance, if and when a product like ours enters the market," said team member Kendal Hirschi, who is a pediatrics and human genetics professor at the Baylor College of Medicine, as well as an associate research director at Texas A&M´s Vegetables and Fruit Improvement Center.

Right now, however, marketability isn´t the prime concern for the lettuce research team - which also includes two more K-State horticulturists, two K-State sensory analysts and the director of environment technologies at Edenspace Systems.

They don´t think their research project is complete. They´re looking into boosting their leaf lettuce´s calcium content further by such methods as adding calcium to the plants´ growing soil and/or immersing the harvested leaves in a calcium-rich solution.

Immersions of calcium have a long history as a post-harvest firming agent. Today, they´re prolonging the shelf life of such fruits and vegetables as apples, cantaloupes, strawberries and carrots.

But, whether they also "up" fresh produce´s calcium content is still an unknown, Park said.

"All we´ve established explicitly so far is that modifying a single plant-calcium transporter will increase calcium content without having a negative impact on lettuce quality. That´s just one step toward getting biofortified lettuce on store shelves. Even so, our scientific approach should now be applicable to numerous other food
crops, too," said Mark Elless of Edenspace, which is newly headquartered in Manhattan, Kan., with its newest research facilities in nearby Junction City, Kan.

An abstract and the research team´s entire report, "Sensory analysis of calcium-biofortified lettuce," is available on the Plant Biotechnology Journal´s Web site at
http://www3.interscience.wiley.com/cgi-bin/fulltext/121451954/HTMLSTART

A colorful outline of Americans´ challenges with calcium -- "The 2004 Surgeon General´s Report on Bone Health and Osteoporosis: What It Means to You" -- is at  http://www.surgeongeneral.gov/library/bonehealth/docs/OsteoBrochure1mar05.pdf.

K-State Research and Extension is a short name for the Kansas State University Agricultural Experiment Station and Cooperative Extension Service, a program designed to generate and distribute useful knowledge for the well-being of Kansans. Supported by county, state, federal and private funds, the program has county Extension offices, experiment fields, area Extension offices and research centers statewide. Its headquarters is on the K-State campus in Manhattan.

Other news from Texas A&M University

 

The U.S. Office of the Surgeon General is projecting that unless
something changes radically and soon, the outcome 11 years from now
for 61.4 million Americans will be problems with low bone mass or
osteoporosis (low bone mass, plus deterioration). That number will
include half of all Americans over age 50 in 2020. It will equal one
in five of the U.S. Census Bureau´s July 2008 population estimate.

The great majority won´t know they have a problem unless or until
they break a bone - typically in hip, wrist or spine. The Surgeon
General expects hip fracture totals to double or even triple by 2040.

Often associated with aging or steroid consumption, weak bones
already lead to 1.5 million fractures each year. Medical expenses
from the osteoporosis-related fractures alone add up to $18 billion.

Another worrisome statistic: A year after today´s annual 300,000 hip
fracture patients leave the hospital, an average 20 percent of them
are dead;. Another 20 percent are in a nursing home, and many of the
rest are so afraid of falling that they´ve become isolated and/or
depressed.

So long as humans are alive, their skeleton is undergoing constant
remodeling. Existing bone tissue breaks down, and its calcium washes
away in the person´s urine. New bone gets deposited, using about 99
percent of what´s made available through the person´s on-going
calcium intake.

As people age, the balance between the break-down and build-up
processes makes some major shifts. Nonetheless, people can work to
promote or keep bone health at any stage of life.

The key ingredients for that work are getting the recommended amounts
of calcium and vitamin D (to help the calcium work) and exercising
both regularly and frequently.

Source: Office of the Surgeon General

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